Abnormal Urodynamic Finding in Monosymptomatic Nocturnal Enuresis.

Document Type : Original Article


Department of Urology, Sohag University Hospital, Sohag, Egypt


To assess the bladder function in patients with monosymptomatic nocturnal enuresis (MNE)
Material and methods: Data was collected from 42 patients with MNE who were referred for urodynamic evaluation at urology department, Sohag University. History and physical examination were done and cystometrogram done for all patients according to International Continence Society Guidelines (ICS).
Results: Urodynamic study was done for 42 patients with MNE, 27 of them were females (64.5%) and 15 males (35.5%). Abnormal cystometric finings was detected in the form of detrusor overactivity in 52.5% and abnormal bladder sensations in 24% of patients
Conclusion: Detrusor overactivity and overactive bladder was detected in more than 50% of MNE. This suggests that overactive bladder play a role in the pathogenesis of MNE and antimuscarnic drugs could be offered as a standard treatment.


1.    Yeung, C.K., et al., Characteristics of primary nocturnal enuresis in adults: an epidemiological study. BJU Int, 2004. 93(3): p. 341-5.
2.    Hjalmas, K., et al., Nocturnal enuresis: an international evidence based management strategy. J Urol, 2004. 171(6 Pt 2): p. 2545-61.
3.    Neveus, T., et al., The standardization of terminology of lower urinary tract function in children and adolescents: report from the Standardisation Committee of the International
 Children''s Continence Society. J Urol, 2006. 176(1): p. 314-24.
4.  De Wachter, S. and J.J. Wyndaele, Does bladder tone influence sensation of filling and electro-sensation in the bladder? A blind controlled study in young healthy volunteers using bethanechol. Journal of Urology, 2001. 165(3): p. 802-804.
5.  Kamperis, K., et al., Nocturnal polyuria in monosymptomatic nocturnal enuresis refractory to desmopressin treatment. Am J Physiol Renal Physiol, 2006. 291(6): p. F1232-40.
6.  Glazier, D.B., et al., Evaluation of the utility of video-urodynamics in children with urinary tract infection and voiding dysfunction. Br J Urol, 1997. 80(5): p. 806-8.
7.    Kosar, A., N. Arikan, and C. Dincel, Effectiveness of oxybutynin hydrochloride in the treatment of enuresis nocturna--a clinical and urodynamic study. Scand J Urol Nephrol, 1999. 33(2): p. 115-8.
8.    Schewe, J., F.H. Brands, and J. Pannek, Voiding dysfunction in children: role of urodynamic studies. Urol Int, 2002. 69(4): p. 297-301.
9.    Ryu, D.S., et al., Role of Urodynamic Study in Nocturnal Enuresis: Urodynamic Findings and Treatment Outcome Correlation in Children with Pharmacotherapy-resistant Monosymptomatic Nocturnal Enuresis or Severe Non-monosymptomatic Nocturnal Enuresis. Low Urin Tract Symptoms, 2014. 6(2): p. 88-93.
10.  Yeung, C.K., et al., Urodynamic findings in adults with primary nocturnal enuresis. J Urol, 2004. 171(6 Pt 2): p. 2595-8.
11.  Charalampous, S., et al., Bladder wall thickness and urodynamic correlation in children with primary nocturnal enuresis. J Pediatr Urol, 2013. 9(3): p. 334-8.