Screening for First Trimester’s Hyperglycemia in High and Low Risk Pregnancy: A Prospective Cohort Study

Document Type : Review Article

Authors

1 obestetric and gynecology department faculty of medicine sohag university

2 obstetric and gynecology department faculty of medicine sohag university

Abstract

Introduction: Hyperglycemia increases the risk of delivering a large for gestational age newborn (LGA) and related complications such as operative delivery, birth trauma and the poor adaptation of the newborn. The aim of this work was to detect cases of hyperglycemia in pregnancy (HIP) as early as possible; this gives the chance to initiate treatment early to achieve euglycemic state during the critical period of organogenesis. Methods: This prospective cohort study carried out on 218 pregnant ladies during their first trimester who were tested for the presence of hyperglycemia. They were divided into two groups: high risk women: (n=96) and low-risk women: (n=122) Results: Fasting blood glucose (FBG), first hour postprandial, 2nd hour postprandial and glycated hemoglobin (HbA1c) in the first and second visit were significantly higher in high risk than low risk (P<0.05). Ten out of those 13 women, blood glucose level could be controlled on diet control and exercise and 3 cases only needed metformin to be added to the regimen all of them were in the high-risk group. FBG and 2hr postprandial were significantly higher in first visit than second visit (P<0.05).

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Sohag Medical Journal
Volume 29, Issue 3
Clinical Science Volume
2025
Pages 94-98

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