Comparative study between Tramadol and Midazolam as an admixture to bupivacaine inUltrasound guided supraclavicular brachial plexus block.

Document Type : Original Article

Authors

1 Department of Anesthesiology, Sohag University, Egypt.

2 Department of Anesthesia, Faculty of Medicine,Sohag University.

Abstract

Background:This is a prospective, randomized, double blind study to evaluate the postoperative analgesia following ultrasound guided supraclavicular brachial plexus block with Tramadol or Midazolam as an admixture to bupivacaine in upper extremity surgery.
Patientsand methods:Total 60 patients of ASA I and II undergoing upper extremity surgery under ultrasound guided brachial plexus block with Bupivacaine were randomly divided in to two groups; one group received Tramadol (1mg/kg) and the other group received midazolam (0.05mg/kg) as an admixture to Bupivacaine. The duration of postoperative analgesia was recorded in both groups using pain VAS score.
Results: The mean duration of postoperative analgesia in the Midazolam group was 650±47.49 minutes while in the tramadol group it was 508±30.44 minutes.
Conclusion: We concluded that midazolamwith local anaesthetic prolongs postoperative analgesiasignificantly than Tramadol (P<0.0001) when used as admixture to local anaesthetic inUltrasound guided brachialplexus block in upper extremity surgery.

Keywords


  1. AnandLK,JindalR(2009). Regional anaesthesia for upper extremity in orthopaedics :areviewarticle.PunjabJ,Orthopaedics 11:1-8.
  2. GebhardRE,Al-SamsamT,GregerJ,etal.Distal nerve block at the wrist for outpatient carpal tunnel surgery offer intraoperative cardiovascular stability and reduce discharge time.AnesthAnalg 2002;95:351. 
  3. Vermeylenk,Engelens,SermusL,SoetensF,Van de veldeM.supraclavicular brachial plexus blocks;review and current practice .ActaAnaesthesiolBelg 2012,63;15-21.
  4. Duma A, Urbanek B, Sitzwohl C, Kreiger A, Zimpfer M, Kapral S. Clonidine as an adjuvant to local anaesthetic axillary brachial plexus block: A randomized, controlled study. Br J Anaesth. 2005;94:112–6.
  5. RobauxS.,Blunt C.,VielF.e, Cuvillon P., Girad F. and Bouaziz H.(2004) Tramadol added to bupivacaine for axillary brachial plexus block improve postoperative analgesia.
  6. Gear, R.W., Miaskowski, C. and Gorden, N.C. (1999) The The Mu receptors tramadol Produces Gender and Dose DependentAnalgesia and Antianalgesia in Patients with Postoperative Pain. Pain, 83, 339-345.
  7. De Tran QH, Clemente A, Doan J, Finlayson RJ (2007). (8): 54. Canadian Journal of Anesthesia. review of approaches and techniques"662–74.
  8. wakhlo ,Woolf CJ: Recent advances in the pathophysiology of acute pain. Br J Anaesth 2006; 63:139-146.