Giardia lamblia affecting humans in Sohag governorate and its related symptoms

Document Type : Original Article

Authors

1 Departments of Medical Parasitology, Faculty of Medicine, Sohag University.

2 Departement of Medical Parasitology, Faculty of Medicine , Sohag University.

3 Department of Medical Parasitology, Faculty of Medicine, Sohag University, Sohag, Egypt.

4 Department of Medical Parasitology, Faculty of Medicine, Sohag University, Egypt.

Abstract

Background and study aim: Giardiasis is a gastrointestinal disease,
caused by the protozoan parasites Giardia lamblia. Thisinfection occurs through ingestion of contaminated water or food by  Giardia lamblia cysts. The aim of this study was to correlate between the presence of Giardia lambilia and different gastrointestinal symptoms.
Subjects and methods: experimental study was performed at the laboratories of Parasitology Department, Faculty of Medicine, Sohag University from October 2016 to October 2017. It was done on 93 patients, who had Giardia from different localities in Sohag governorate after examination by saline and iodine wet mount. History taking and questionnaire survey about gastrointestinal symptoms was followed.
Results: Diarrhea was the first complaint that affected all cases, abdominal colic was the second most common complaint affecting 84 (90.3 %) cases, followed by failure to thrive affecting 32 (34.5 %) cases, followed by abdominal distension affecting 26 (28 %) cases, and vomiting affecting 6 (6.6 %) of cases.
Conclusion: We concluded that However diarrhea was the first complaint that affected all cases, abdominal colic was the second most common complaint affecting 84 (90.3 %) cases, followed by failure to thrive affecting 32 (34.5 %) cases, followed by abdominal distension affecting 26 (28 %) cases, and vomiting affecting 6 (6.6 %) of cases. 

Keywords


  1. Adam, R. D. (2001). Biology of Giardia lamblia. Clin Microbiol Rev.
    14(3), 447-475.
  2. Yason,  J. A. D. L. and  Rivera,  W.L.  (2007).  Genotyping  of  Giardia duodenalis isolates  among  residents  of  slum  area  in  Manila, Philippines. Parasitol. Res., 101(3), 681–687.  
  3. Daly, E. R. , Roy, S. J., Blaney, D. D., Manning, J. S., Hill, V. R., Xiao, L.  and  Stull,  J. W.  (2010).  Outbreak  of  giardiasis  associated  with  a community drinking water source. Epidemiol. Infect., 138(4), 491–500 .
  4. Balcioglu, I. C. E., Limoncu, P., Ertan, K., Yereli, A., Ozbilginve, A. and Onag, A. (2003). Incidence  of  giardiasis  among  siblings  in  Turkey. Pediatr. Int, 45 (3), 311–313.  
  5. Duffy, T. L., Montenegro-Bethancourt, G.,  Solomons, N. W., Belosevic, M. and Clandinin, M. T. (2013). Prevalence of giardiasis in children  attending  semi-urban  daycare  centres  in  Guatemala  and comparison of 3 Giardia detection tests. J. Health Popul. Nutr. 31 (2), 290–293 .
  6. Escobedo, A. A., Almirall, P., Alfonso, M., Cimerman, S.  and Chacin-Bonilla, L. (2014). Sexual transmission of giardiasis: a neglected route of spread? Acta Trop. 132, 106–111.
  7. Ryan, U.  and  Caccio, S. M. (2013): Zoonotic potential of GiardiaInt. J. Parasitol. 43 (12-13): 943–956.
  8. Julio, C.,Vilares, A.,Oleastro, M., Ferreira, I., Gomes, S.,Monteiro, L.,Nunes, B.,Tenreiro, R., and Angelo, H. (2012): Prevalence and risk factors for Giardia duodenalis infection among children: A case study in Portugal. Parasites & Vectors, 27 (5):22-29.
  9. Mohran, (2013): Genotyping of Giardia lamblia in human and animal feces in Qaliopia governate. thesis. Benha university.
  10. De Lucio, A., Martínez-Ruiz, R., Merino, F.J., Bailo, B., Aguilera, M., Fuentes, I., and Carmena, D. (2015): Molecular genotyping of Giardia duodenalis isolates from symptomatic individuals attending two major public hospitals in Madrid, Spain. PLoS One 10 (12): e0143981.
  11. Duldova, A. Juris, P. Jurisova, S. Jarcuska, P. and Krcmery, v. (2016): Epidemiology and geographical distribution of gastrointestinal parasitic infection in humans in Slovakia. Helminthologia. 53 (4): 309 – 317.
  12. Bernard N. and Samuel B. N. (2011): Giardia lamblia: a major parasitic cause of childhood diarrhoea in patients attending a district hospital in Ghana. Parasit Vectors. 4 (1): 163-170.
  13. Heehong, S., Davaasuren, A., Young, J., Davaajav, A., Shin-Hyeong, C., Won-Ja, L. and Sang-Eun, L. (2014): Molecular characterization of Giardiaduodenalis and Cryptosporidium parvum in fecal samplesof individuals in Monogolia. Am. J. Trop. Med. Hyg. 90 (1): 43-47.
  14. El-Badry A.A., Mohammed, A.F., Abdul Gawad, E. (2017): Predominance of Giardia intestinalis assemblage B in diarrhoeic children in Sharkia, Egypt. Parasitologists United Journal. ISSN: 1687-7942, Vol. 10, No. 1 & 2.
  15. Gelanew, T., Lalle, M.,Hailu, A., Pozio, E. and Caccio, S.M. (2007): Molecular characterization of human isolates of Giardia duodenalis from Ethiopia. Acta Trop. 102 (2): 92–99.
  16. Al-Mohammed, H.I. (2011): Genotypes of Giardiaintestinalis clinical isolates of gastrointestinal symptomatic and asymptomatic Saudi children. Parasitol. Res, 108 (6): 1375–1381.
  17. Puebla, L.J., Nunez, F.A., García, A.B., Rivero, L.R., Millan, I.A., and Prado, R.C. (2017): Prevalence of  Giardia duodenalis among children from a central region of Cuba: molecular characterization and associated risk factors. J. Parasit. Dis. 41(2): 405–413.
  18. Eligo-Garcia, L. Galvan, S. and Jimenez-Cardoso, E. (2002): phylogenetic distance between Giardia intestinalis isolates from symptomatic and asymptomatic children. Rev. Invest.Clin. 54 (2): 113-118.
  19. Abd-El Hafed, W.M. (2010): Polymerase chain reaction (PCR)and direct stool examination techniques, in diagnosis of Giardia lamblia infection. M.Sc. Thesis. Faculty of Medicine. Benha University.
  20. Lebbad, M., Petersson, I., Karlsson, L., Botero-Kleiven, S., Andersson, J.O., Svenungsson, B., and Svärd, S.G., (2011): Multilocus genotyping of human Giardia isolates suggests limited zoonotic transmission and association between assemblage B and flatulence in children. PLoS Negl. Trop. Dis. 5 (8): e1262.
  21. Misra, S.P., Vatsala, A.H., Dwivedi, J.K., Manisha, L.A. and Singh, P.A. (2006): Giardia lamblia trophozoites in gastric biopsies of patients with gastric carcinoma and duodenal ulcer. Indi. J. Microbiol., 49 (4): 519-523.