Cardiac Markers in scorpion envenomed children in some hospitals in Sohag.

Document Type : Original Article

Authors

1 department of Pediatric , Faculty of Medicine, Sohag University, Sohag, Egypt.

2 Department, Faculty of Medicine, Sohaguniversit, Sohag, Egypt.

3 Department of clinical and chemical pathology, Sohag Faculty of Medicine, Sohag University.

4 Department of Pediatric , Faculty of Medicine, Sohag University, Sohag, Egypt.

Abstract

Background:Scorpionism is an endemic health problem in Upper Egypt.This study shows theepidemiological,clinical and laboratory manifestations of scorpion envenomation and identify factors that are predictive of severe cases.
Methods: Prospective  study had been performed at Emergency Unit in the Sohag  university  hospital  and Sohag General Hospital from January to  December , 2016. It included  50 patients with definite history of scorpion sting envenomation.Theepidemiological,clinical,andlaboratory findings of patientswererecorded.
Results: We found that 44% had abnormal serum troponin and 58% had abnormal serum CKmb.  Also 54% had abnormal serum lactate dehydrogenase and 44% had abnormal serum myoglobin.  ECG study revealed changes in the severe group in the form of low QRS, ST segment change, sinus tachycardia and ventricular ectopics. Severe group showed significant reduction in the %SF and LVEF in the comparison to the mild/moderate group.
Conclusions:The present study is  demonstrated that cTnI is a highly specific and sensitive indicator for myocardial injury and adverse outcome in victims of scorpion envenomation.  So cTnI may be used in these cases for both diagnosis and prognosis. The use of cTnI in the immediate assessment of patients with severe systemic envenomation appears warranted to identify those at risk of myocardial injury.

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