Cognitive outcome of traumatic brain injury in elderly patients

Document Type : Original Article

Authors

1 Department of Neurosurgery , Faculty of Medicine, Sohag University.

2 Department of public health and community medicine, Faculty of Medicine, Sohag University.

3 Department of Neurosurgery , Faculty of Medicine, Assuit University.

Abstract

Objective: To assess the cognitive outcome of traumatic brain injury in elderly patients.
Design: a prospective study.
Methodsthis study was conducted on 50 elderly patients exposed to TBI in sohag university hospital and 50 patients exposed to TBI but less than 65 years used as a control.
IntroductionTraumatic brain injury (TBI) is a significant problem in older adults,and is associated with changes in the brain that affect the cognition(Sapoznik et al 2006)
ResultsDuring the study period, 50 elderly patients with TBI were followed up for cognitive outcome, 12 patients (24%) were associated with cognitive deficits.
Conclusion: TBI in elderly patients is associated with cognitive deficits post injury

Keywords

References

1- Kempermann, G., Gast, D., & Gage, F. H. (2002). Neuroplasticity in old age: Sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Annals of Neurology, 52(2), 135–143                    
2- Patel HC, Bouamra O, Woodford M, et al (2010). Clinical article: mortality associated with severe head injury in the elderly. ActaNeurochir (Wien). (2010).                                     
3- Sapoznik, S., Ivenshitz, M., & Segal, M. (2006). Age-dependent glutamate induction of synaptic plasticity in cultured hippocampal neurons. Learning and Memory, 13(6), 719-727.                         
4- Senathi-Raja, D., Ponsford, J., & Schonberger, M. (2010). The association of age and time postinjury with long-term emotional outcome following traumatic brain injury. Journal of Head Trauma and Rehabilitation, 25(5), 330-338.                
5- Wheelen-Goodinson, R., Ponsford, J. L., Schonberger, M., & Johnston, L. (2010). Predictors of psychiatric disorders following traumatic brain injury. Journal of Head Trauma and Rehabilitation, 25(5), 320-3.
Sohag Medical Journal
Volume 22, Issue 1
January 2018
Pages 11-13

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