Use of Transient Elastography in Assessment of Non Alcoholic Fatty Liver Disease

Abd Elrahman, Noha Mohamed; Galal, Ghada Moustafa; Abd El Hamid, Ramy Mamdouh; Sayed, Sherif A.

doi:10.21608/smj.2023.238958.1418

Use of Transient Elastography in Assessment of Non Alcoholic Fatty Liver Disease

Document Type : Review Article

Authors

¹ Gastroenterology, faculty of Medicine, Sohag University

² Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assuit University.

³ tropical medicine and gastroentrology , sohag university hospital

⁴ Clinical&amp;chemical pathology department faculty of medicine Sohag university

10.21608/smj.2023.238958.1418

Abstract

Abstract:

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. It is associated with obesity, type 2 diabetes, dyslipidemia, and is commonly regarded as the hepatic component of metabolic syndrome. It includes: simple fatty liver; and non-alcoholic steatohepatitis (NASH), which may progress to cirrhosis. Liver biopsy is the gold standard for the diagnosis of NASH to differentiate simple bland steatosis but it is invasive and expensive. It is important to develop new methods to assess NAFLD, the presence or absence of NASH and the severity of any complicating fibrosis or cirrhosis. In this review we will demonstrate the use of Transient Elastography (TE) as a non invasive tool to differentiate between simple steatosis and the advanced disease with fibrosis.

Aim of the work:

To shed some light on the clinical utility of Fibroscan as a non invasive imaging technique for assessment and diagnosis of NAFLD and elucidate its possible limitations.

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