Eerectile dysfunction patients who are phospho diestrase enzyme type 5 inhibitors (PDE5Is) non responders: A review article.

Document Type : Original Article

Authors

1 Dermatology 'venerology 'andrology, Faculty of medicine, Sohag university

2 Department of Dermatology, Venereology, and Andrology, Sohag Faculty of Medicine. Sohag University.

3 Department of Dermatology, Venereology, and Andrology, Sohag Faculty of Medicine. Sohag University.DERMATOLOGY, Venereology and Andrology, Faculty of Medicine , sohag university

Abstract

Erectile dysfunction (ED) has many definitions, one of these accepted definition that the male is unable to initiate and/or preserve an erection for ideal sexual intercourse satisfying for both partners. There are many lines for ED treatment, oral phosphodiesterase type 5 inhibitors (PDE5Is) represent the corner stone for ED treatment. Intra cavernous injections, vacuum constriction device & surgical implantation of penile prosthesis are another methods for ED treatment. Authors failed to define exactly the failure of PDE5-I therapy in ED. However, many reviews reported two types of PDE5Is non responders. As regard the cause making ED patients non responders to PDE5Is, multiple etiological factors have a role. Four strategies were reported about in literatures as trial to solve PDE5i non responders problem including lifestyle adjustments, psychological assessment, comorbidities treatment & non drug therapeutic interventions.Patient counseling to know and resolve patients' concerns and ensure the hopped success of treatment. Good communication and regular follow up should be established.

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Sohag Medical Journal
Volume 27, Issue 1 - Serial Number 1
Clinical Science Volume
2023
Pages 32-36

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