Efficacy of diamond microdermabrasion with topical vitamin C in treatment of acne scars

Document Type : Original Article

Authors

1 Department of Dermatology, Faculty of Medicine, Sohag University.

2 Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Sohag University.

Abstract

Introduction: Post acne scars are a common avoidable complication of acne vulgaris. The face is the most common site affected by acne vulgaris and scars so that it has an important impact on the quality of life of these patients.
 Treatment of these scars is so important for acne patients but although different treatment methods are available no single treatment has been universally effective. Microdermabrasion (MDA) with infusion is a new modification of MDA technology that includes exfoliation with a dermal infusion.
During this procedure, topical products are introduced into the skin at the time of or immediately after exfoliation.
Aim of the work: Evaluation of efficacy of diamond microdermabrasion with topical vitamin  C in the treatment of acne scars.
Patients and Methods: Ten patients with atrophic post-acne scars in the face attending the outpatient clinic of  Dermatology in Sohag University Hospitals between April 2018 to September 2018 were subjected to six diamond microdermabrasion sessions plus administration of topical vit. C (during the session of diamond microdermabrasion and daily topical application in between sessions). The sessions of diamond microdermabrasion were two weeks apart. patients were evaluated at each session and one month after completion of sessions for both efficacy and safety of the procedure.
Results: The mean ± SD of the patients' age in the study were 26.00 ±5.81years old. Nine females and one male with a mean duration of acne scars ± SD7.45±4.73 years, 80%% of patients suffered psychological distress from their acne scars. At the end of the study duration, none of the patients achieved grade reduction in their Goodman and Baron qualitative grading score and 100% of patients had poor ( <25%) satisfaction.
Conclusion: Multiple  sessions of diamond  microdermabrasion with topical vitamin C during sessions and daily application is an ineffective treatment for post-acne atrophic scars

Keywords

Main Subjects

References

1.   Admani S, Barrio VR. Evaluation and treatment of acne from infancy to preadolescence. Dermatologic therapy. 2013;26(6):462-6.
2.   Fabbrocini G, Annunziata MC, D'Arco V, De Vita V, Lodi G, Mauriello MC, et al. Acne scars: pathogenesis, classification and treatment. Dermatology research and practice. 2010;2010:893080.
3.   Layton AM, Henderson CA, Cunliffe WJ. A clinical evaluation of acne scarring and its incidence. Clinical and experimental dermatology. 1994;19(4):303-8.
4.   Cunliffe WJ, Gould DJ. Prevalence of facial acne vulgaris in late adolescence and in adults. British medical journal. 1979;1(6171):1109-10.
5.  Midwood KS, Williams LV, Schwarzbauer JE. Tissue repair and the dynamics of the extracellular matrix. The international journal of biochemistry & cell biology. 2004;36(6):1031-7.
6.  Kravvas G, Veitch D, Al-Niaimi F. The increasing relevance of biofilms in common dermatological conditions. The Journal of dermatological treatment. 2017:1-6.
7. Lee, Shen, Kuo-Hsien, Hu CH and  Fang : Lasers and   microdermabrasion enhance and control topical delivery of vitamin C. J Invest Dermatol.2003;121:1118–1125
8. Lee, Tsai, Fang, Liu, Hu CH and  Fag: Micro-dermabrasion as a novel tool to enhance drug delivery via the skin: an animal study. Dermatol Surg.2006; 32:1013–102.
9. Shim  , Barnette , Hughes  and Greenway:  Microdermabrasion: a clinical and histopathologic study. Dermatol Surg.2001;27(6):524–530.
10. Darius Karimipour, Gholamreza Karimipour and  Jeffrey  Orringer Microdermabrasion: An Evidence-Based Review. Plast. Reconstr. Surg.2010; 125: 372.
11.  Oresajo C, Stephens T, Hino PD, Law RM, Yatskayer M, Foltis P, et al. Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin. Journal of cosmetic dermatology. 2008;7(4):290-7.
12. Chen L, Hu JY, Wang SQ. The role of antioxidants in photoprotection: a critical review. Journal of the American Academy of Dermatology. 2012;67(5):1013-24.
13.  Sauermann K, Jaspers S, Koop U, Wenck H. Topically applied vitamin C increases the density of dermal papillae in aged human skin. BMC dermatology. 2004;4(1):13.
14.  Goodman GJ, Baron JA. Postacne scarring: a qualitative global scarring grading system. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 2006;32(12):1458-66.
15.  Leheta T, El Tawdy A, Abdel Hay R, Farid S. Percutaneous collagen induction versus full-concentration trichloroacetic acid in the treatment of atrophic acne scars. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 2011;37(2):207-16.
16.  Sharad J. Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin. Journal of cosmetic dermatology. 2011;10(4):317-23.
17.  El-Domyati M, Barakat M, Awad S, Medhat W, El-Fakahany H, Farag H. Microneedling Therapy for Atrophic Acne Scars: An Objective Evaluation. The Journal of clinical and aesthetic dermatology. 2015;8(7):36-42.
18.  Gadkari R, Nayak C. A split-face comparative study to evaluate efficacy of combined subcision and dermaroller against combined subcision and cryoroller in treatment of acne scars. Journal of cosmetic dermatology. 2014;13(1):38-43.
19.   Leheta TM, Abdel Hay RM, El Garem YF. Deep peeling using phenol versus percutaneous collagen induction combined with trichloroacetic acid 20% in atrophic post-acne scars; a randomized controlled trial. The Journal of dermatological treatment. 2014;25(2):130-6.
20. Coimbra M, Rohrich RJ, Chao J, Brown SA. A prospective controlled assessment of microdermabrasion for damagedskin and fine rhytides. Plast Reconstr Surg. 2004;113:1438–1443; discussion 1444.
21.Karimipour DJ, Kang S, Johnson TM, et al. Microdermabrasion: A molecular analysis following a single treatment. J Am Acad Dermatol. 2005;52:215–223.
22.Majid I. Microneedling therapy in atrophic facial scars: an objective assessment. Journal of cutaneous and aesthetic surgery. 2009;2(1):26-30.
23. Chawla S. Split Face Comparative Study of Microneedling with PRP Versus Microneedling with Vitamin C in Treating Atrophic Post Acne Scars. Journal of cutaneous and aesthetic surgery. 2014;7(4):209-12.
24.  Nofal E, Helmy A, Nofal A, Alakad R, Nasr M. Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study. Dermatologic surgery: official publication for American Society for Dermatologic Surgery [et al]. 2014;40(8):864-73.
25. Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV, Walker LC, et al. Topical L-ascorbic acid: percutaneous absorption studies. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 2001;27(2):137-42.
26.  Matsuda S, Shibayama H, Hisama M, Ohtsuki M, Iwaki M. Inhibitory effects of a novel ascorbic derivative, disodium isostearyl 2-O-L-ascorbyl phosphate on melanogenesis. Chemical & pharmaceutical bulletin. 2008;56(3):292-7.
 
 
 
 
Sohag Medical Journal
Volume 23, Issue 1
January 2019
Pages 189-194

Files

Share

How to cite

Statistics